Clotrimazole/betamethasone dipropionate

Clotrimazole/betamethasone dipropionate
Combination of
ClotrimazoleAzole antifungal
Betamethasone dipropionateCorticosteroid
Names
Trade namesLotrisone
Clinical data
WHO AWaReUnlinkedWikibase error: ⧼unlinkedwikibase-error-statements-entity-not-set⧽
Routes of
use		Topical
External links
AHFS/Drugs.comProfessional Drug Facts
Legal
License data
Legal status
Identifiers
CAS Number
  • 23593-75-1 checkY
  • 5593-20-4 checkY
UNII
KEGG
ATC code

Clotrimazole/betamethasone dipropionate, sold under the brand name Lotrisone among others, is a topical medication for the treatment of fungal infections of the feet, groin, and body in people 17 years of age and older.[1] It is a combination of clotrimazole and betamethasone dipropionate.[1] It is applied to the skin.[1]

Common side effects include paresthesia, rash, edema, and secondary infections.[1]

In 2017, it was the 300th most commonly prescribed medication in the United States, with more than one million prescriptions.[2][3]

Medical uses

Clotrimazole/betamethasone dipropionate is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in people 17 years of age and older.[1]

History

Clotrimazole/betamethasone dipropionate cream was approved for use in the United States in July 1984,[4] and the lotion was approved for use in the United States in December 2000.[5]

Society and culture

Cost

In 2017, it was the 300th most commonly prescribed medication in the United States, with more than one million prescriptions.[2][3]

  • Betamethasone Dipropionate/Clotrimazole costs (US)
    Betamethasone Dipropionate/Clotrimazole costs (US)
  • Betamethasone Dipropionate/Clotrimazole prescriptions (US)
    Betamethasone Dipropionate/Clotrimazole prescriptions (US)

References

  1. 1 2 3 4 5 "Lotrisone- clotrimazole and betamethasone dipropionate cream". DailyMed. 14 June 2019. Archived from the original on 28 August 2021. Retrieved 13 April 2020.
  2. 1 2 "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
  3. 1 2 "Betamethasone Dipropionate; Clotrimazole - Drug Usage Statistics". ClinCalc. 23 December 2019. Archived from the original on 12 April 2020. Retrieved 11 April 2020.
  4. ↑ "Lotrisone: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Archived from the original on 1 October 2020. Retrieved 13 April 2020.
  5. ↑ "Drug Approval Package: Lotrisone (Clotrizazole & Betamethasone Dipropionate) NDA #020010". U.S. Food and Drug Administration (FDA). 8 September 2004. Archived from the original on 7 April 2021. Retrieved 13 April 2020.


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