3-Hydroxyaspartic acid

3-Hydroxyaspartic acid
Names
	Preferred IUPAC name (2S)-2-Amino-3-hydroxybutanedioic acid
	Other names (2S)-2-Amino-3-hydroxysuccinic acid; 3-Hydroxyaspartic acid; Beta-hydroxyaspartic acid
Identifiers
CAS Number	1860-87-3 ;
3D model (JSmol)	Interactive image; Interactive image;
ChEBI	CHEBI:10696 ;
ChemSpider	391503 ;
IUPHAR/BPS	4497;
KEGG	C11511 ;
PubChem CID	443239;
	InChI InChI=1S/C4H7NO5/c5-1(3(7)8)2(6)4(9)10/h1-2,6H,5H2,(H,7,8)(H,9,10)/t1-,2-/m0/s1 Key: YYLQUHNPNCGKJQ-LWMBPPNESA-N ; InChI=1/C4H7NO5/c5-1(3(7)8)2(6)4(9)10/h1-2,6H,5H2,(H,7,8)(H,9,10)/t1-,2-/m0/s1 Key: YYLQUHNPNCGKJQ-LWMBPPNEBT;
	SMILES C(C(C(=O)O)O)(C(=O)O)N; O=C(O)[C@@H](N)[C@H](O)C(=O)O;
Properties
Chemical formula	C4H7NO5
Molar mass	149.102 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

3-Hydroxyaspartic acid (three letter abbreviation: Hya) also known as beta-hydroxyaspartic acid is derivative of aspartic acid which has been hydroxylated at position-3. The adjacent image shows L-threo-3-Hydroxyaspartate. The Hya amino acid residue is sometimes contained in EGF-like domains such as Vitamin K-dependent coagulation plasma proteins including protein C.^[1]

References

↑ Castellino FJ, Ploplis VA, Zhang L (2008). "Γ-Glutamate and β–Hydroxyaspartate in Proteins". gamma-Glutamate and beta-hydroxyaspartate in proteins. Methods Mol. Biol. Vol. 446. pp. 85–94. doi:10.1007/978-1-60327-084-7_6. ISBN 978-1-58829-719-8. PMID 18373251.

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[pmid18373251-1] Castellino FJ, Ploplis VA, Zhang L (2008). "Γ-Glutamate and β–Hydroxyaspartate in Proteins". gamma-Glutamate and beta-hydroxyaspartate in proteins. Methods Mol. Biol. Vol. 446. pp. 85–94. doi:10.1007/978-1-60327-084-7_6. ISBN 978-1-58829-719-8. PMID 18373251.

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