National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Florid cemento-osseous dysplasia

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Other Names:
florid osseous dysplasia; focal cemento-osseous dysplasia
Categories:
Florid cemento-osseous dysplasia (FCOD) is a condition that occurs in the jaw bone, especially close to where the teeth are formed.[1][2] People with FCOD develop lesions in the jaw, were spots of normal bone are replaced with a mix of connective tissue and abnormal bone.[1][3] The lesions are often found in equal numbers and size on both sides of the jaw. People with FCOD rarely have symptoms and it is usually found with dental x-rays during a routine dental examination.

The cause of FCOD is unknown, and it does not usually run in families. It mainly occurs in middle aged women of African American and Asian descent.[1][2] The number, size, and shape of the lesions can be different from person to person. Occasionally the lesions expand or get infected and may cause discomfort, pain, or mild disfigurement.[1][2] Treatment for this condition is observation and avoiding infections of the mouth and teeth. The long-term outlook for people with FCOD is good. 
Last updated: 11/14/2018
Usually florid cemento-osseous dysplasia causes no symptoms. It is often found by accident while getting dental x-rays for some other purpose.[2] Occasionally however, the lesions get infected and may expand causing discomfort, pain, and/or mild disfigurement.[2]
Last updated: 11/14/2018
The cause of florid cemento-osseous dysplasia (FCOD) is not known.[1][2] 
Last updated: 11/14/2018
Florid cemento-osseous dysplasia (FCOD) doesn't typically run in families. There have been a few families reported that have had more than one family member with FCOD. In these families, the condition occurs at younger ages and the lesions grow faster than in FCOD seen in people with no family history of the condition.[2][4]
Last updated: 11/14/2018
Diagnosis of florid cemento-osseous dysplasia (FCOD) relies on the x-ray findings of the lesions as well as the clinical signs and symptoms. FCOD can look like other, more serious conditions, and it's important to make sure that FCOD is the correct diagnosis.[2] Other conditions that can look like FCOD include: 
Last updated: 11/14/2018
In most people, florid cemento-osseous dysplasia (FCOD) does not require treatment. People with this condition should be followed with dental x-rays every 2-3 years.[2][3][4] In addition, because infections are difficult to treat in people with FCOD, sometimes people with FCOD take antibiotics to help prevent infections.  If someone with FCOD does get an infection of the jaw, treatment may include surgery to clean out the infection.[2]
Last updated: 11/14/2018
People with florid cemento-osseous dysplasia (FCOD) do not usually have any symptoms from their condition. FCOD makes people more likely to get infections in the teeth and jaw. It is difficult to treat those infections with antibiotics and surgery may be necessary to remove the infection.[2] The long-term outlook for people with this condition is generally good. 
Last updated: 11/14/2018
Florid cemento-osseous dysplasia (FCOD) usually African-American women in their mid-40s.[1][2][4] Asian women are more likely to develop this condition, but both men and women of other ethnicities have been reported with FCOD. While the exact prevalence is unknown, the literature reports that about 5.5% of black women may have FCOD.[4]
Last updated: 11/14/2018

If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. You may find these specialists through advocacy organizations, clinical trials, or articles published in medical journals. You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments.

If you can’t find a specialist in your local area, try contacting national or international specialists. They may be able to refer you to someone they know through conferences or research efforts. Some specialists may be willing to consult with you or your local doctors over the phone or by email if you can't travel to them for care.

You can find more tips in our guide, How to Find a Disease Specialist. We also encourage you to explore the rest of this page to find resources that can help you find specialists.

Healthcare Resources

Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.

Clinical Research Resources

  • The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders. For more information about applying to the research study, please visit their website.

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Florid cemento-osseous dysplasia. Click on the link to view a sample search on this topic.

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  1. Das BK, Das SN, Gupta A, Nayak S. Florid cemento-osseous dysplasia. Jl Oral Maxillofac Pathol. Jan-Apr, 2013; 17(1):150-159. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687180.
  2. Fenerty S, Shaw W, Verma R, Syed AB, Kuklani R, Yang J, Ali S. Florid cemento-osseous dysplasia: review of an uncommon fibro-osseous lesion of the jaw with important clinical implications. Skeletal Radiol. 2017; 46(5):581-590. https://www.ncbi.nlm.nih.gov/pubmed/28194495.
  3. Aiuto R, Gucciardino F, Rapetti R, Siervo S, Bianchi A-E. Management of symptomatic florid cemento-osseous dysplasia: Literature review and a case report. J Clin Exp Dent. 2018; 10(3):e29105. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923893.
  4. Consolaro A, Paschoal SRB, Ponce JB, Miranda DAO. Florid cemento-osseous dysplasia: a contraindication to orthodontic treatment in compromised areas. Dental Press J Orthod. May-June, 2018; 23(3):26-34. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072450/pdf.