National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Immunotactoid glomerulopathy

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If you have a kidney transplant from a living donor, what are the chances of this disease attacking the new kidney? What is the long-term prognosis of this disease? I can find very little information.
The long-term prognosis for immunotactoid glomerulopathy is difficult to predict due to the rarity of the condition, but some studies suggest that 50% of patients will have end-stage kidney disease (ESKD) by 5 years after diagnosis. Patients with ESKD may either pursue dialysis or kidney transplantation. The disease may recur in the transplanted kidney. However, the degree and rate of recurrence remains unclear due to the rarity of this disease. Researchers believe the rate of progression of the disease in the transplanted kidney is slower than in the native kidney. The rate of recurrence seems to be higher in patients who have monoclonal gammopathy.[1][2]
Last updated: 3/28/2014

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  1. Immunotactoid Glomerulopathy. UNC Health Care Kidney Center. http://www.unckidneycenter.org/kidneyhealthlibrary/immunotactoid.html. Accessed 3/28/2014.
  2. Fervenza F, Sethi S, Appel G. Glomerular diseases due to nonamyloid fibrillar deposits. UpToDate. July 16, 2014; http://www.uptodate.com/contents/glomerular-diseases-due-to-nonamyloid-fibrillar-deposits. Accessed 8/19/2015.