National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Anonychia congenita


Other Names:
Isolated congenital anonychia; Autosomal recessive nonsyndromic congenital nail disorder-4; Nonsyndromic congenital nail disorder, 4; Isolated congenital anonychia; Autosomal recessive nonsyndromic congenital nail disorder-4; Nonsyndromic congenital nail disorder, 4; Congenital anonychia See More
Subtypes:
The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.
orphanet

Orpha Number: 79143

Definition
Isolated congenital anonychia is characterized by nail abnormalities ranging from onychodystrophy (dystrophic nails) to anonychia (absence of nails). Onychodystrophy-anonychia has been described in at least four generations of a family with male-to-male transmission, suggesting autosomal dominant transmission. Anonychia has been described in approximately less than 20 cases; it is likely to be transmitted as an autosomal recessive trait. Total anonychia congenita, in which all the fingernails and toenails are absent, may have an autosomal dominant inheritance pattern.

Visit the Orphanet disease page for more resources.
Last updated: 5/1/2007

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In-Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

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