Mendelian susceptibility to mycobacterial diseases

Question Question

How might mendelian susceptibility to mycobacterial diseases be classified?

Answer Answer

MSMD is classified into the following subtypes:^[1]

Interferon-Gamma receptor deficiencies:

Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete IFNgammaR1 deficiency
Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete IFNgammaR2 deficiency
Autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR1 deficiency
Autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR2 deficiency
Autosomal recessive mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR1 deficiency
Autosomal recessive mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR2 deficiency.

Last updated: 4/6/2016

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

Please see our Disclaimer.

References References

Mendelian susceptibility to mycobacterial diseases: Specific defects. UpToDate. April 17, 2015; http://www.uptodate.com/contents/mendelian-susceptibility-to-mycobacterial-diseases-specific-defects.