National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Bier spots



Other Names:
Physiologic anaemic macules; Angiospastic macules; Exaggerated physiologic speckled mottling of skin

Bier spots are a benign vascular anomaly characterized by white spots on the skin surrounded by a pale halo of erythema (redness). They are more common on the arms, the legs and the trunk. They are better observed when a tourniquet is placed around the affected arm or leg, and become less obvious when raising it.[1][2] The spots are thought to be due to raised pressure constricting small veins (venous hypertension) and in most cases no cause is found (idiopathic).[1] Bier spots usually affect healthy people, and may appear during pregnancy. But sometimes, they are part of a systemic disease such as cryoglobulinaemia, polycythaemia, scleroderma, aortic hypoplasia and coarctation, alopecia areata, Peutz-Jeghers syndrome, lichen planus, rapid heartbeat (tachycardia), lymphedema and excessive sweating of the hands (palmar hyperhidrosis).[1][2] They are usually, self-limiting and except for counseling, require no treatment.[2][3]
Last updated: 6/1/2016

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  1. Liaw FY & Chiang CP. Bier spots. CMAJ. April 16, 2013; 185(7):http://www.cmaj.ca/content/185/7/E304.full.
  2. Mahajan VK, Khatri G, Singh R, Chauhan PS & Mehta KS. Bier spots: An uncommon cause of mottled skin. Indian Dermatology Online Journal. 2015; 6(2):128–129. http://doi.org/10.4103/2229-5178.153020.
  3. Vascular malformations associated with steal phenomena. DermNet NZ. 2015; http://www.dermnetnz.org/vascular/steal.html.