National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Telangiectasia macularis eruptive perstans


Other Names:
Telangiectasia macularis eruptiva perstans; Paucicellular mastocytosis; Telangiectatic cutaneous mastocytosis
This disease is grouped under:
Telangiectasia macularis eruptive perstans (TMEP) is a very rare skin disease.  Some researchers consider it a rare subtype of cutaneous mastocytosis. The lesions of TMEP typically appear as small, irregular red spots and brown widened blood vessels on the skin (telangiectasia) mostly located on the trunk, legs, and arms in a symmetrical pattern. The palms, soles and face are spared in most cases. In most cases, the lesions are not itchy and do not form blisters. Rarely, there are other symptoms in other parts of the body.  Diagnosis is usually based on the features, and confirmed by a skin biopsy.[1][2] Treatment includes medication such as antihistamines and cromoglycates.[1] 
Last updated: 7/30/2016

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

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Medical Terms Other Names
Learn More:
HPO ID
80%-99% of people have these symptoms
Cutaneous mastocytosis 0200151
Hypermelanotic macule
Hyperpigmented spots
0001034
Papule 0200034
Pruritus
Itching
Itchy skin
Skin itching
[ more ] 		0000989
Skin plaque 0200035
30%-79% of people have these symptoms
Cardiac arrest
Heart stops beating
0001695
Diarrhea
Watery stool
0002014
Dyspnea
Trouble breathing
0002094
Headache
Headaches
0002315
Nausea and vomiting 0002017
Rhinitis
Nasal inflammation
0012384
5%-29% of people have these symptoms
Skin nodule 0200036
Telangiectasia of the skin 0100585
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Last updated: 7/1/2020

Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.

Conditions with similar signs and symptoms from Orphanet
The diagnosis is usually straightforward but misdiagnosis as chronic urticaria or idiopathic anaphylaxis has been reported.
Visit the Orphanet disease page for more information.

Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.

Organizations Supporting this Disease

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
    Orphanet
    Orphanet

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  1. Castells MC and Akin C. Mastocytosis (cutaneous and systemic): Epidemiology, pathogenesis, and clinical manifestations. UpToDate. December 5, 2016; http://www.uptodate.com/contents/mastocytosis-cutaneous-and-systemic-epidemiology-pathogenesis-and-clinical-manifestations.
  2. Watkins CE, Bokor WB, Leicht S, Youngberg G & Krishnaswamy G. Telangiectasia macularis eruptiva perstans: more than skin deep. Dermatology Reports. 2011; 3(1):12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211494/.