National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Hematohidrosis



Other Names:
Hematidrosis

Hematohidrosis is a rare condition characterized by blood oozing from intact skin and mucosa. Signs and symptoms include sweating blood, crying bloody tears, bleeding from the nose, bleeding from the ears, or oozing blood from other skin surfaces. The episodes are usually self-limiting. In some cases, the fluid appears to be blood tinged, while others resemble frank blood. It can occur on any part of the body, but most commonly appears on the face (ear, nose, and eyes). The cause is unknown. The bleeding is due to the rupture of the very small blood vessels of the skin (dermal capillaries).[1] Some theories include increased vascular pressure leading to the passage of blood cells through the ducts of the sweat glands, inflammation of the vessels of the skin (vasculitis of dermal vessels), and intensified sympathetic activation.[2] Some cases are associated with systemic disease, bleeding disorders, menstruation, excessive exertion, high blood pressure, fear and intense emotional stress.[1][2][3][4] Treatment remains a challenge, and may include vitamin C, hemostatic drugs, anxiolytics, or antidepressants, and propranolol.[1][2][3] Resolution of symptoms may occur spontaneously.[1]
Last updated: 10/31/2016

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hematohidrosis. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles


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  1. Jafar A, & Ahmad A. Child Who Presented with Facial Hematohidrosis Compared with Published Cases. CaseReports in Dermatological Medicine. 781.. 2016; 2016:5095781. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808663/.
  2. Uber M & cols. Hematohidrosis: insights in the pathophysiology. Int J Dermatol. December, 2015; 54(12):e542-3. https://www.ncbi.nlm.nih.gov/pubmed/26227471.
  3. Khalid SR, Maqbool S, Raza N, Mukhtar T, Ikram A & Qureshi S. Ghost spell or hematohidrosis. J Coll Physicians Surg Pak. April, 2013; 23(4):293-4. https://www.ncbi.nlm.nih.gov/pubmed/23552544.
  4. Deshpande M, Indla V, Kumar V, Reddy IR. Child who presented with hematohidrosis (sweating blood) with oppositional defiant disorder. Indian J Psychiatry. 2014; 56:289-91. http://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2014;volume=56;issue=3;spage=289;epage=291;aulast=Deshpande.