National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Diphallia


Other Names:
Diphallus
Categories:
The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.
orphanet

Orpha Number: 227

Definition
A rare, non-syndromic, urogenital tract malformation characterized by complete or partial penile duplication, ranging from only glans duplication to the presence of two penis shafts with either one (i.e. bifid phallus) or two (i.e. true diphallia) corpora cavernosum in each. Additional anomalies, such as urethra duplication, an abnormal voiding pattern, hypo- or epispadias, bifid/ectopic scrotum, bladder exstrophy or duplication, are frequently associated, but it may also present as an isolated anomaly. In severe cases, pubic symphysis diastasis, imperforate or duplicated anus, colon/ rectosigmoidal duplication, inguinal hernia and vertebral anomalies may be observed.

Visit the Orphanet disease page for more resources.
Last updated: 2/1/2019

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

Showing of 25 |
Medical Terms Other Names
Learn More:
HPO ID
80%-99% of people have these symptoms
Bifid penis
Penile duplication
0100599
Bifid scrotum
Cleft of scrotum
0000048
30%-79% of people have these symptoms
Anal atresia
Absent anus
0002023
Distal urethral duplication 0008706
Ectopic scrotum
Abnormal scrotum position
0030275
Hypospadias 0000047
Penoscrotal transposition 0100600
5%-29% of people have these symptoms
Abnormal spermatogenesis 0008669
Abnormality of the pubic bone
Abnormality of the pubic bones
Abnormality of the pubis
[ more ] 		0003172
Atrial septal defect
An opening in the wall separating the top two chambers of the heart
Hole in heart wall separating two upper heart chambers
[ more ] 		0001631
Bladder exstrophy 0002836
Cloacal exstrophy 0010475
Cryptorchidism
Undescended testes
Undescended testis
[ more ] 		0000028
Epispadias 0000039
Horseshoe kidney
Horseshoe kidneys
0000085
Inguinal hernia 0000023
Renal duplication
Extra kidney
0000075
Renal malrotation
Abnormal rotation of the kidneys
0004712
Ureteral duplication
Double ureter
0000073
1%-4% of people have these symptoms
Absent thumb
Absent thumbs
0009777
Butterfly vertebrae 0003316
Duplicated colon 0005223
Hemivertebrae
Missing part of vertebrae
0002937
Rectoperineal fistula 0004792
Scoliosis 0002650
Showing of 25 |
Last updated: 7/1/2020

Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.

Clinical Research Resources

  • Orphanet lists European clinical trials, research studies, and patient registries enrolling people with this condition. 

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know.