National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Hypertrichosis lanuginosa, acquired


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The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.
orphanet

Orpha Number: 2221

Definition
A rare cutaneous paraneoplastic disease characterized by the presence of excessive lanugo-type hair on the glabrous skin of face, neck, trunk and limbs that can be associated with additional clinical features such as burning glossitis, papillary hypertrophy of the tongue, diarrhea, dysgeusia, and/or weight loss. It is associated with lymphoma or cancer of the gastrointestinal system, urinary tract, lung, breast, uterus or ovary.

Visit the Orphanet disease page for more resources.
Last updated: 2/1/2012

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

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Medical Terms Other Names
Learn More:
HPO ID
80%-99% of people have these symptoms
Abnormal eyebrow morphology
Abnormality of the eyebrow
0000534
Abnormal eyelid morphology
Abnormality of the eyelid
Abnormality of the eyelids
[ more ] 		0000492
Fine hair
Fine hair shaft
Fine hair texture
Thin hair shaft
Thin hair texture
[ more ] 		0002213
Generalized hirsutism
Excessive hairiness over body
0002230
Hypopigmentation of hair
Loss of hair color
0005599
30%-79% of people have these symptoms
Glossitis
Inflammation of the tongue
Smooth swollen tongue
[ more ] 		0000206
Macroglossia
Abnormally large tongue
Increased size of tongue
Large tongue
[ more ] 		0000158
5%-29% of people have these symptoms
Acanthosis nigricans
Darkened and thickened skin
0000956
Chronic diarrhea 0002028
Ichthyosis 0008064
Lymphadenopathy
Swollen lymph nodes
0002716
Neoplasm of the breast
Breast tumor
Tumours of the breast
[ more ] 		0100013
Neoplasm of the respiratory system
Respiratory system tumor
0100606
Ovarian neoplasm
Ovarian tumor
0100615
Poor appetite
Decreased appetite
0004396
Weight loss 0001824
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Last updated: 7/1/2020

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

Where to Start

  • DermNet New Zealand is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • The Merck Manual provides information on this condition for patients and caregivers. 

In-Depth Information

  • The Merck Manual for health care professionals provides information on Hypertrichosis lanuginosa, acquired.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

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