Skin macules tend to be the earliest symptom in multisystem disease. Small bowel involvement is very common, and Degos disease can cause intestinal perforation (tear).[2] Intestinal perforation is a medical emergency which requires prompt treatment. Click here to learn more about the signs and symptoms of intestinal perforation. Unfortunately intestinal disease tends to recur in these individuals.
Degos disease can also affect the nervous system, in particular the cerebral and peripheral nerves. This may result in a variety of symptoms, such as partial paralysis, aphasia (difficulty communicating), cranial neuropathies (which affect nerves that are connected with the brain and control sight, eye movement, hearing, and taste), sensory disturbances, andThis table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
| Medical Terms | Other Names | Learn More: HPO ID |
|---|---|---|
| 80%-99% of people have these symptoms | ||
| Dermal atrophy |
Skin degeneration
|
0004334 |
| Papule | 0200034 | |
| Telangiectasia of the skin | 0100585 | |
| 30%-79% of people have these symptoms | ||
| Abdominal pain |
Pain in stomach
Stomach pain
[ more ]
|
0002027 |
| Fatigue |
Tired
Tiredness
[ more ]
|
0012378 |
| Gastrointestinal hemorrhage |
Gastrointestinal bleeding
|
0002239 |
| Gastrointestinal infarctions |
Death of digestive organ tissue due to poor blood supply
|
0005244 |
| Intestinal perforation | 0031368 | |
| Muscle flaccidity | 0010547 | |
| Nausea and vomiting | 0002017 | |
| Weight loss | 0001824 | |
| 5%-29% of people have these symptoms | ||
| Abnormal myocardium morphology | 0001637 | |
| Abnormal pericardium morphology | 0001697 | |
| Abnormality of the lower urinary tract | 0010936 | |
| Abnormality of the optic nerve |
Optic nerve issue
|
0000587 |
| Amaurosis fugax | 0100576 | |
| Arterial thrombosis |
Blood clot in artery
|
0004420 |
| Arteritis |
Inflammation of artery
|
0012089 |
|
Clouding of the lens of the eye
Cloudy lens
[ more ]
|
0000518 | |
| Chest pain | 0100749 | |
| Cranial nerve paralysis | 0006824 | |
| Diplopia |
Double vision
|
0000651 |
| Intestinal fistula | 0100819 | |
| Ischemic stroke | 0002140 | |
| Migraine |
Intermittent migraine headaches
Migraine headache
Migraine headaches
[ more ]
|
0002076 |
| Myocardial infarction |
Heart attack
|
0001658 |
| Pain insensitivity | 0007021 | |
| Peritonitis | 0002586 | |
| Pleural effusion |
Fluid around lungs
|
0002202 |
|
Drooping upper eyelid
|
0000508 | |
| Respiratory failure | 0002878 | |
| Seizure | 0001250 | |
| Vertigo |
Dizzy spell
|
0002321 |
| Percent of people who have these symptoms is not available through HPO | ||
| Abnormal conjunctiva morphology | 0000502 | |
| 0000006 | ||
| Constrictive pericarditis | 0002563 | |
| Stroke | 0001297 | |
If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. You may find these specialists through advocacy organizations, clinical trials, or articles published in medical journals. You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments.
If you can’t find a specialist in your local area, try contacting national or international specialists. They may be able to refer you to someone they know through conferences or research efforts. Some specialists may be willing to consult with you or your local doctors over the phone or by email if you can't travel to them for care.
You can find more tips in our guide, How to Find a Disease Specialist. We also encourage you to explore the rest of this page to find resources that can help you find specialists.
Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.
|
Conditions with similar signs and symptoms from Orphanet
|
|---|
|
The histology of early lesions resembles cutaneous lupus erythematosus (see this term). More developed lesions can imitate lichen sclerosus (see this term).
Visit the
Orphanet disease page
for more information.
|
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know.
