This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
Medical Terms | Other Names | Learn More: HPO ID |
---|---|---|
80%-99% of people have these symptoms | ||
Oculomotor nerve palsy | 0012246 | |
Short palpebral fissure |
Short opening between the eyelids
|
0012745 |
Cross-eyed
Squint
Squint eyes
[ more ]
|
0000486 | |
30%-79% of people have these symptoms | ||
Abnormal vertebral segmentation and fusion | 0005640 | |
Anteverted nares |
Nasal tip, upturned
Upturned nasal tip
Upturned nose
Upturned nostrils
[ more ]
|
0000463 |
Blepharophimosis |
Narrow opening between the eyelids
|
0000581 |
Deeply set eye |
Deep set eye
Deep-set eyes
Sunken eye
[ more ]
|
0000490 |
Low posterior hairline |
Low hairline at back of neck
|
0002162 |
Sensorineural hearing impairment | 0000407 | |
5%-29% of people have these symptoms | ||
Abnormal form of the vertebral bodies | 0003312 | |
Abnormal pupil morphology |
Abnormality of the pupil
Pupillary abnormalities
Pupillary abnormality
[ more ]
|
0000615 |
Abnormality of cardiovascular system morphology | 0030680 | |
Absent radius |
Missing outer large bone of forearm
|
0003974 |
Amblyopia |
Lazy eye
Wandering eye
[ more ]
|
0000646 |
Aniridia |
Absent iris
|
0000526 |
Anorectal anomaly | 0012732 | |
Aplasia/Hypoplasia of the thumb |
Absent/small thumb
Absent/underdeveloped thumb
[ more ]
|
0009601 |
Blepharospasm |
Eyelid spasm
Eyelid twitching
Involuntary closure of eyelid
Spontaneous closure of eyelid
[ more ]
|
0000643 |
Short fingers or toes
|
0001156 | |
Camptodactyly |
Permanent flexion of the finger or toe
|
0012385 |
Central heterochromia | 0007818 | |
Chorioretinal coloboma |
Birth defect that causes a hole in the innermost layer at the back of the eye
|
0000567 |
Cleft roof of mouth
|
0000175 | |
Ectopic kidney |
Abnormal kidney location
Displaced kidney
[ more ]
|
0000086 |
Everted lower lip vermilion |
Drooping lower lip
Outward turned lower lip
[ more ]
|
0000232 |
External ear malformation | 0008572 | |
Facial asymmetry |
Asymmetry of face
Crooked face
Unsymmetrical face
[ more ]
|
0000324 |
Global |
0001263 | |
Hypopigmented skin patches |
Patchy loss of skin color
|
0001053 |
Hypoplasia of the radius |
Underdeveloped outer large forearm bone
|
0002984 |
Hypoplastic iris stroma | 0007990 | |
Iris coloboma |
Cat eye
|
0000612 |
Irregular hyperpigmentation | 0007400 | |
Abnormally small skull
Decreased circumference of cranium
Decreased size of skull
Reduced head circumference
Small head circumference
[ more ]
|
0000252 | |
Microcornea |
Cornea of eye less than 10mm in diameter
|
0000482 |
Little lower jaw
Small jaw
Small lower jaw
[ more ]
|
0000347 | |
Narrow internal auditory canal | 0011386 | |
Involuntary, rapid, rhythmic eye movements
|
0000639 | |
Optic disc hypoplasia | 0007766 | |
Patchy hypopigmentation of hair | 0011365 | |
Plagiocephaly |
Flat head syndrome
Flattening of skull
Rhomboid shaped skull
[ more ]
|
0001357 |
Preauricular skin tag | 0000384 | |
Preaxial hand |
Extra thumb
|
0001177 |
Drooping upper eyelid
|
0000508 | |
0001250 | ||
Short neck |
Decreased length of neck
|
0000470 |
Skeletal muscle atrophy |
Muscle degeneration
Muscle wasting
[ more ]
|
0003202 |
Spina bifida occulta | 0003298 | |
Stenosis of the external auditory canal |
Narrowing of passageway from outer ear to middle ear
|
0000402 |
Talipes equinovarus |
Club feet
Club foot
Clubfeet
Clubfoot
[ more ]
|
0001762 |
Triphalangeal thumb |
Finger-like thumb
|
0001199 |
Webbed neck |
Neck webbing
|
0000465 |
Wide nasal bridge |
Broad nasal bridge
Broad nasal root
Broadened nasal bridge
Increased breadth of bridge of nose
Increased breadth of nasal bridge
Increased width of bridge of nose
Increased width of nasal bridge
Nasal bridge broad
Wide bridge of nose
Widened nasal bridge
[ more ]
|
0000431 |
More detailed information about the treatment of Duane syndrome is available on Medscape Reference's Web site and can be viewed here. You may need to register to view this information, but registration is free.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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I have isolated Duane retraction syndrome. My left has retracted inward towards the nose and it appears smaller than the right. The last few years it really bothers me. I was wondering if there is anything I could do about it. I usually close my big eye a little bit so that they can appear even, but recently I noticed my left eye closing even more. This problem only increases with my left eye getting smaller over the years and it makes a really bad image of my face. If there is anything you can tell me that helps my condition I would be grateful. See answer
Duane syndrome affects my left eye. I have constant ringing in my left ear and neck pain when I look over my left shoulder. Are these issues related to Duane syndrome? My doctors did not know the answer. See answer
My daughter has Duane retraction syndrome. She is also left-handed and has very small ears and ear lobes. No one else on my side of the family, or her father's, have these signs. When her father was younger he experimented with LSD. I don't know how many times he took the drug. I remember hearing years ago that people who have taken LSD might have offspring with missing chromosomes. Has this been verified as being one cause of the major missing chromosome for DRS? See answer
I was born with Duane syndrome. Now I am close to the stage of deciding to have children. What are the chances of my children being born with Duane syndrome? See answer
Can in vitro fertilization cause Duane syndrome? See answer
I have Duane syndrome. These is no known family history. What the probability of passing this condition on to any future offspring? See answer
If a first child is affected by Duane syndrome, what is the likelihood that subsequent children will also be affected? Should genetic counseling be done prior to attempting a second pregnancy? See answer