National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Glucose-6-phosphate dehydrogenase deficiency



My brother has glucose 6 phosphate dehydrogenase (G6PD) deficiency. Most of the information I have found regarding this condition relates to children and infants. How can I find information specific to adults with this condition? How is this condition managed?


How might glucose-6-phosphate dehydrogenase (G6PD) deficiency be treated?

The most important aspect of management for G6PD deficiency is to avoid agents that might trigger an attack. In cases of acute hemolytic anemia, a blood transfusion or even an exchange transfusion may be required.[1]

The G6PD Deficiency Association, which is an advocacy group that provides information and supportive resources to individuals and families affected by G6PD deficiency, provides a list of drugs and food ingredients that individuals with this condition should avoid. They also maintain a list of low risk drugs that are generally safe to take in low doses.
Last updated: 1/23/2014

How can I find information specific to adults with glucose 6 phosphate dehydrogenase (G6PD) deficiency?

You can find relevant journal articles on glucose 6 phosphate dehydrogenase deficiency specific to adults through a service called PubMed, a searchable database of medical literature. Information on finding an article and its title, authors, and publishing details is listed here.  Some articles are available as a complete document, while information on other studies is available as a summary abstract.  To obtain the full article, contact a medical/university library (or your local library for interlibrary loan), or order it online using the following link. Using "glucose 6 phosphate dehydrogenase deficiency[ti] AND adults" as your search term should locate articles. To narrow your search, click on the "Limits" tab under the search box and specify your criteria for locating more relevant articles.  Click here to view a search.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

The National Library of Medicine (NLM) Web site has a page for locating libraries in your area that can provide direct access to these journals (print or online). The Web page also describes how you can get these articles through interlibrary loan and Loansome Doc (an NLM document-ordering service). You can access this page at the following link http://nnlm.gov/members/. You can also contact the NLM toll-free at 888-346-3656 to locate libraries in your area.

Last updated: 1/18/2017

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

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  1. Joly D. Glucose-6-phosphate-dehydrogenase deficiency. Orphanet. May 2009; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=362.