Pars planitis

Vision loss and reduced visual acuity associated with pars planitis may occur due to a variety of factors including epiretinal membrane, macular edema, clouding of the fluid in the center of the eye, inflammation of blood vessels in the eye (vasculitis), and cataracts. Some studies suggest that it is best to treat inflammation in pars planitis quickly and completely to reduce the chance of complications that may affect vision clarity and that, in some cases, treatment can help to restore vision. Unfortunately, some severely affected people may experience progressive vision loss despite appropriate treatment.^[1][2]

The first approach to treating pars planitis is corticosteroid eye drops or injections near the eye to control inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs, including aspirin) or steroid medications (such as prednisone) can be taken by mouth. If these strategies are not successful, other medications may be given to reduce the body's immune response (medications called immunosuppressants, such as methotrexate).^[3][4] 

If medications are not effective, surgery may be considered. Cryotherapy has been performed in affected people to remove eye tissue that has inflammation. Although this surgery has been shown to be effective in restoring clarity of vision, there are concerns that it may cause damage to other parts of the eye. Another surgery, known as vitrectomy, can be done to remove cloudy fluid (vitreous humor) from the eye.^[1][3]