National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

HTLV-1 associated myelopathy/tropical spastic paraparesis



Is there treatment or a cure for HAM/TSP or for HTLV-1 in general?


How might human T-cell leukemia virus, type 1 be treated? 

No cure or treatment exists for human T-cell leukemia virus, type 1 (HTLV-1). Management is focused on early detection and preventing the spread of HTLV-1 to others. Screening blood doners, promoting safe sex and discouraging needle sharing can decrease the number of new infections. Mother-to-child transmission can be reduced by screening pregnant women so infected mothers can avoid breastfeeding.[1][2]
Last updated: 12/10/2014

Is there research being conducted on possible treatment options for human T-cell lymphotrophic virus associated myelopathy/tropical spastic paraparesis (HAM/TSP)?

The U.S. National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. To find trials enrolling people with HAM/TSP, click here. After you click on a study, review its "eligibility" criteria to determine its appropriateness. Use the study’s contact information to learn more. Check the ClinicalTrials.gov Web site often for regular updates.

If you are interested in enrolling in a clinical trial, you can find helpful general information on clinical trials by clicking here.

A tutorial about clinical trials that can also help answer your questions can be found at the following link from the National Library of Medicine:
http://www.nlm.nih.gov/medlineplus/tutorials/clinicaltrials/htm/video.htm
Last updated: 12/1/2014

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

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  1. David T Scadden, MD; Andrew R Freedman, FRCP; Paul Robertson, MRCP. Human T-lymphotropic virus type I: Disease associations, diagnosis, and treatment. UpToDate. March 2014;
  2. HTLV Type I and Type II. NORD. May 2012; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1203/viewAbstract.