National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Drug induced dyskinesia

Not a rare disease Not a rare disease
Other Names:
Dyskinesia, drug induced
Subtypes:
Drug induced dyskinesia is an involuntary movement disorder. Signs and symptoms include repetitive and irregular motions of the mouth, face, limbs and/or trunk.[1] Treatment with antipsychotic drugs and levodopa (commonly used to treat Parkinson disease) are well recognized causes of drug-induced dyskinesia.[1][2][3] Dyskinesia develops in around 40% of people with Parkinson's disease who have been on levodopa treatment for four to six years.[3] Tardive dyskinesia is a severe form of drug-induced dyskinesia due to antipsychotic treatments. Tardive dyskinesia develops in 5% of people per year of treatment.[2]
Last updated: 10/22/2013
The following medications have caused drug-induced dyskinesia in some individuals:[1][4]

  • Levodopa
  • Chlorpromazine
  • Fluphenazine
  • Haloperidol
  • Trifluoperazine
  • Flunarizine (Sibelium)
  • Metoclopramide
  • Prochlorperazine
Last updated: 10/22/2013

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Drug induced dyskinesia. Click on the link to view a sample search on this topic.

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  • What drugs cause drug induced dyskinesia? See answer


  1. Loonen AJ, Ivanova SA. New insights into the mechanism of drug-induced dyskinesia. CNS Spectr. 2013 Feb;18(1):15-20; http://www.ncbi.nlm.nih.gov/pubmed/23593652. Accessed 10/22/2013.
  2. Akbostanci MC, Atbasoglu EC, Balaban H. Tardive dyskinesia, mild drug-induced dyskinesia, and drug-induced parkinsonism: risk factors and topographic distribution. Acta Neurol Belg. 1999 Sep;99(3):176-81; http://www.ncbi.nlm.nih.gov/pubmed/10544725. Accessed 10/22/2013.
  3. Damier P. Drug-induced dyskinesias. Curr Opin Neurol. 2009 Aug;22(4):394-9; http://www.ncbi.nlm.nih.gov/pubmed/19491677. Accessed 10/22/2013.
  4. Tardive dyskinesia. MedlinePlus. May 21, 2012; http://www.nlm.nih.gov/medlineplus/ency/article/000685.htm. Accessed 10/22/2013.