National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Benign mesonephroma



Other Names:
Wolffian adnexal tumor; WAT; Female adnexal tumor of probable Wolffian origin; Wolffian adnexal tumor; WAT; Female adnexal tumor of probable Wolffian origin; FATWO; Wolffian adenoma; Mesonephric adenoma; Wolffian duct adenoma; Wolffian tumor See More
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Benign mesonephroma (Wolffian tumors or Wolffian duct adenomas) are rare tumors located anywhere along the length between the ovary and vagina in sites of remnant wolffian ducts. Wolffian ducts are structures in a developing embryo that get incorporated into the reproductive system in males and degenerate in females. Wolffian tumors are thought to have a low potential to become cancerous and tend to range from 0.8 to 25 centimeters in size.[1] Surgery is the recommended treatment. In a small number of cases, recurrences or malignancy have been been reported. Close follow-up is advised.[2]
Last updated: 4/13/2015

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Organizations Supporting this Disease


These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Benign mesonephroma. Click on the link to view a sample search on this topic.

Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question

  • I've had a recurrence of a wolffian tumor. Is there a way I can talk to other women with this condition. Also, is there any research studies enrolling women with this tumor? See answer



  1. Ramirez PT, Wolf JK, Malpica A, Deavers MT, Liu J, Broaddus R. Wolffian duct tumors: case reports and review of the literature. Gynecol Oncol. Aug 2002; 86(2):225-30. http://www.ncbi.nlm.nih.gov/pubmed/12144833. Accessed 4/13/2015.
  2. Gupta AK, Srinivasan R, Nijhawan R. Female adnexal tumor of probable Wolffian origin.. Indian J Pathol Microbiol. Oct-Dec 2014; 57(4):620-2. http://www.ncbi.nlm.nih.gov/pubmed/25308022. Accessed 4/13/2015.