(+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)

(+)-α-Santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) (EC 4.2.3.50, SBS) is an enzyme with systematic name (2Z,6Z)-farnesyl diphosphate lyase (cyclizing; (+)-α-santalene-forming).[1] This enzyme catalyses the following chemical reaction

(2Z,6Z)-farnesyl diphosphate (+)-α-santalene + diphosphate
(+)-α-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)
Identifiers
EC no.4.2.3.50
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-farnesyl diphosphate.

References

  1. Sallaud C, Rontein D, Onillon S, Jabès F, Duffé P, Giacalone C, Thoraval S, Escoffier C, Herbette G, Leonhardt N, Causse M, Tissier A (January 2009). "A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites". The Plant Cell. 21 (1): 301–17. doi:10.1105/tpc.107.057885. PMC 2648096. PMID 19155349.
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