Sulfolactate sulfo-lyase

The enzyme (2R)-sulfolactate sulfo-lyase (EC 4.4.1.24) catalyzes the reaction

(2R)-3-sulfolactate pyruvate + hydrogensulfite
(2R)-Sulfolactate sulfo-lyase
Identifiers
EC no.4.4.1.24
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is (2R)-3-sulfolactate hydrogensulfite-lyase (pyruvate-forming). Other names in common use include Suy, SuyAB, and 3-sulfolactate bisulfite-lyase.[1][2][3]

References

  1. Graham DE, White RH (April 2002). "Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics". Natural Product Reports. 19 (2): 133–47. doi:10.1039/b103714p. PMID 12013276.
  2. Rein U, Gueta R, Denger K, Ruff J, Hollemeyer K, Cook AM (March 2005). "Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA". Microbiology. 151 (Pt 3): 737–47. doi:10.1099/mic.0.27548-0. PMID 15758220.
  3. Denger K, Cook AM (March 2010). "Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase". Microbiology. 156 (Pt 3): 967–74. doi:10.1099/mic.0.034736-0. PMID 20007648. S2CID 15332564.


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