1,3-Propanedisulfonic acid

1,3-Propanedisulfonic acid is a sulfonic acid containing two sulfonate units. Its salts are called eprodisates and have been evaluated as a protector of renal function in AA amyloidosis.[2]

1,3-Propanedisulfonic acid
Names
Preferred IUPAC name
Propane-1,3-disulfonic acid
Other names
Eprosidate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.204.148
UNII
  • InChI=1S/C3H8O6S2/c4-10(5,6)2-1-3-11(7,8)9/h1-3H2,(H,4,5,6)(H,7,8,9)
    Key: MGNVWUDMMXZUDI-UHFFFAOYSA-N
  • C(CS(=O)(=O)O)CS(=O)(=O)O
Properties
C3H8O6S2
Molar mass 204.21 g·mol−1
Melting point 120–125 °C (248–257 °F; 393–398 K)[1]
Boiling point 157 °C (315 °F; 430 K)[1]
Hazards
GHS labelling:
GHS05: CorrosiveGHS07: Exclamation mark
Danger
H302, H312, H314, H332
P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. McElvain, S. M.; Jelinek, Arthur; Rorig, Kurt (September 1945). "Ethane-1,2- and Propane-1,3-disulfonic Acids and Anhydrides". Journal of the American Chemical Society. 67 (9): 1578–1581. doi:10.1021/ja01225a053.
  2. Rumjon, Adam; Coats, Thomas; Javaid, Muhammad M (24 February 2012). "Review of eprodisate for the treatment of renal disease in AA amyloidosis". International Journal of Nephrology and Renovascular Disease. 5: 37–43. doi:10.2147/IJNRD.S19165. ISSN 1178-7058. PMC 3304340. PMID 22427728.


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