2,3-Bis(acetylmercaptomethyl)quinoxaline

2,3-Bis(acetylmercaptomethyl)quinoxaline is an antiviral agent which can inhibits poliovirus RNA synthesis in vitro and in vivo and inhibits human herpesvirus 1 multiplication in vitro. It does not interfere with attachment, penetration or DNA synthesis, but interrupts a late stage in virus assembly and/or maturation.[1][2]

2,3-Bis(acetylmercaptomethyl)­quinoxaline
Names
Preferred IUPAC name
S,S′-[Quinoxaline-2,3-diylbis(methylene)] di(ethanethioate)
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C14H14N2O2S2/c1-9(17)19-7-13-14(8-20-10(2)18)16-12-6-4-3-5-11(12)15-13/h3-6H,7-8H2,1-2H3
    Key: KIYGADXCTZZZDG-UHFFFAOYSA-N
  • InChI=1/C14H14N2O2S2/c1-9(17)19-7-13-14(8-20-10(2)18)16-12-6-4-3-5-11(12)15-13/h3-6H,7-8H2,1-2H3
    Key: KIYGADXCTZZZDG-UHFFFAOYAA
  • CC(=O)SCC1=NC2=CC=CC=C2N=C1CSC(=O)C
Properties
C14H14N2O2S2
Molar mass 306.40 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Bucchini, Danielle; Girard, Marc (1975–1976). "Inhibition of Herpes Simplex Virus Multiplication by 2,3-Bis(Acetyl Mercaptomethyl)-Quinoxalin". Intervirology. 6 (4–5): 285–95. doi:10.1159/000149482. PMID 186437.
  2. Mahy, Brian W J (2001). A dictionary of virology (3. ed.). San Diego, Calif. [u.a.]: Academic Press. pp. 2. ISBN 0-12-465327-8.


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