2,6-Dichloropyridine

2,6-Dichloropyridine is an organohalide with the formula C5H3Cl2N. A white solid, it is one of six isomers of dichlorpyridine. It serves as a precursor to the antibiotic enoxacin.[1] 2,6-Dichoropyridine is produced by direct reaction of pyridine with chlorine. 2-Chloropyridine is an intermediate.[1]

2,6-Dichloropyridine
Names
Preferred IUPAC name
2,6-Dichloropyridine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.017.531
EC Number
  • 219-282-3
UNII
  • InChI=1S/C5H3Cl2N/c6-4-2-1-3-5(7)8-4/h1-3H
    Key: FILKGCRCWDMBKA-UHFFFAOYSA-N
  • C1=CC(=NC(=C1)Cl)Cl
Properties
C5H3Cl2N
Molar mass 147.99 g·mol−1
Melting point 86–89 °C (187–192 °F; 359–362 K)
Boiling point 211–212 °C (412–414 °F; 484–485 K)
Hazards
GHS labelling:
GHS06: ToxicGHS07: Exclamation mark
Danger
H301, H315, H319, H335
P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Toxicity

The LD50 is 115 mg/kg (oral, mice).[1]

References

  1. Shimizu, Shinkichi; Watanabe, Nanao; Kataoka, Toshiaki; Shoji, Takayuki; Abe, Nobuyuki; Morishita, Sinji; Ichimura, Hisao (2007). "Pyridine and Pyridine Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a22_399.
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