2'-hydroxydaidzein reductase
In enzymology, a 2'-hydroxydaidzein reductase (EC 1.3.1.51) is an enzyme that catalyzes the chemical reaction
- 2'-hydroxy-2,3-dihydrodaidzein + NADP+ 2'-hydroxydaidzein + NADPH + H+
| 2'-hydroxydaidzein reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.51 | ||||||||
| CAS no. | 126125-01-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 2'-hydroxy-2,3-dihydrodaidzein and NADP+, whereas its 3 products are 2'-hydroxydaidzein, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase. Other names in common use include NADPH:2'-hydroxydaidzein oxidoreductase, HDR, and 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. This enzyme participates in isoflavonoid biosynthesis.
References
- Fischer D, Ebenau-Jehle C, Grisebach H (1990). "Phytoalexin synthesis in soybean: purification and characterization of NADPH:2'-hydroxydaidzein oxidoreductase from elicitor-challenged soybean cell cultures". Arch. Biochem. Biophys. 276 (2): 390–5. doi:10.1016/0003-9861(90)90737-J. PMID 2306102.
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