3-Bromothiophene
3-Bromothiophene is an organosulfur compound with the formula C4H3BrS. It is a colorless liquid. It is a precursor to the antibiotic timentin and the vasodilator cetiedil.[1]
![]() | |
Names | |
---|---|
Preferred IUPAC name
3-Bromothiophene | |
Other names
3-Thienyl bromide, 3BT | |
Identifiers | |
3D model (JSmol) |
|
ChemSpider | |
ECHA InfoCard | 100.011.656 |
EC Number |
|
PubChem CID |
|
UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
Properties | |
C4H3BrS | |
Molar mass | 163.03 g·mol−1 |
Appearance | Colorless liquid |
Density | 1.74 g/mL |
Melting point | −10 °C (14 °F; 263 K) |
Boiling point | 150–158 °C (302–316 °F; 423–431 K) |
Immiscible | |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
N,Xi,Xn,T |
GHS labelling: | |
![]() ![]() ![]() ![]() | |
Danger | |
H226, H301, H310, H315, H317, H319, H330, H335, H411 | |
P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P272, P273, P280, P284, P301+P310, P302+P350, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P320, P321, P322, P330, P332+P313, P333+P313, P337+P313, P361, P362, P363, P370+P378, P391, P403+P233, P403+P235, P405, P501 | |
Flash point | 56 °C (133 °F; 329 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
Preparation
Unlike 2-bromothiophene, the 3-bromo isomer cannot be prepared directly from thiophene. It can be prepared by debromination of 2,3,5-tribromothiophene,[2] which is obtained by bromination of thiophene.
![Synthese van 3-broomthiofeen](../I/Synthesis_3-Bromothiophene.svg.png.webp)
Synthese van 3-broomthiofeen
See also
References
- Jonathan Swanston (2006). "Thiophene". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a26_793.pub2.
- S. Gronowitz (1959). "3-Bromothiophene". Org. Syntheses. 44: 9. doi:10.15227/orgsyn.044.0009.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.