3-Hydroxyasparagine
3-Hydroxyasparagine also known as β-hydroxyasparagine (beta-hydroxyasparagine) is a modified asparagine amino acid. It appears in posttranslational modification of cbEGF-like domains which can occur in humans and other Eukaryotes. The amino acid code used for this is Hyn. The modified amino acid residue is found in fibrillin-1.[1] This amino acid is also found in urine.[2]
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IUPAC name
3-Hydroxyasparagine | |
Other names
β-Hydroxyasparagine | |
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ChEBI | |
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Properties | |
C4H8N2O4 | |
Molar mass | 148.118 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
- Glanville, RW; Qian, RQ; McClure, DW; Maslen, CL (28 October 1994). "Calcium binding, hydroxylation, and glycosylation of the precursor epidermal growth factor-like domains of fibrillin-1, the Marfan gene protein". The Journal of Biological Chemistry. 269 (43): 26630–4. doi:10.1016/S0021-9258(18)47065-2. PMID 7929395.
- Barrett, Graham (2012). Chemistry and Biochemistry of the Amino Acids. Springer Science & Business Media. p. 80. ISBN 9789400948327.
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