3-methyleneoxindole reductase
In enzymology, a 3-methyleneoxindole reductase (EC 1.3.1.17) is an enzyme that catalyzes the chemical reaction
- 3-methyl-1,3-dihydroindol-2-one + NADP+ 3-methylene-1,3-dihydro-2H-indol-2-one + NADPH + H+
3-methyleneoxindole reductase | |||||||||
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Identifiers | |||||||||
EC no. | 1.3.1.17 | ||||||||
CAS no. | 37255-29-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are 3-methyl-1,3-dihydroindol-2-one and NADP+, whereas its three products are 3-methylene-1,3-dihydro-2H-indol-2-one, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase. This enzyme is also termed 3-methyloxindole:NADP+ oxidoreductase.
References
- Moyed HS, Williamson V (1967). "Multiple 3-methyleneoxindole reductases of peas, differential inhibition by synthetic auxins". J. Biol. Chem. 242 (5): 1075–7. PMID 6021071.
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