3-Succinoylsemialdehyde-pyridine dehydrogenase
3-Succinoylsemialdehyde-pyridine dehydrogenase (EC 1.2.1.83) is an enzyme with systematic name 4-oxo-4-(pyridin-3-yl)butanal:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- 4-oxo-4-(pyridin-3-yl)butanal + NADP+ + H2O 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H+
| 3-Succinoylsemialdehyde-pyridine dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.83 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme has been characterized from the soil bacterium Pseudomonas sp. HZN6.
References
- Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W (April 2012). "Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine". Applied and Environmental Microbiology. 78 (7): 2154–60. doi:10.1128/AEM.07025-11. PMC 3302611. PMID 22267672.
External links
- 3-succinoylsemialdehyde-pyridine+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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