4-(γ-Glutamylamino)butanoic acid

4-(γ-Glutamylamino)butanoic acid
Names
	Preferred IUPAC name 2-Amino-5-[(4-hydroxy-4-oxobutyl)amino]-5-oxopentanoic acid
	Systematic IUPAC name 4-Amino-5-((3-carboxypropyl)amino)-5-oxopentanoic acid
	Other names 2-Amino-5-(3-carboxypropylamino)-5-oxopentanoic acid[1]; 4-(Glutam-5-ylamino)butanoic acid; γ-Glutamyl-γ-aminobutyric acid;
Identifiers
CAS Number	5105-96-4 S ;
3D model (JSmol)	Interactive image;
Abbreviations	Glutamyl-GABA; Glu-GABA; γ-Glutamyl-GABA; γ-Glu-γ-Abu;
Beilstein Reference	2418119
ChEBI	CHEBI:49260 ;
ChEMBL	ChEMBL269574 ;
ChemSpider	315618 ;
KEGG	C15767 ;
PubChem CID	355553; 23724570 S;
CompTox Dashboard (EPA)	DTXSID90965336 ;
	InChI InChI=1S/C9H16N2O5/c10-6(9(15)16)3-4-7(12)11-5-1-2-8(13)14/h6H,1-5,10H2,(H,11,12)(H,13,14)(H,15,16) Key: MKYPKZSGLSOGLL-UHFFFAOYSA-N ;
	SMILES NC(CCC(=O)NCCCC(O)=O)C(O)=O;
Properties
Chemical formula	C9H16N2O5
Molar mass	232.236 g·mol−1
log P	−1.434
Acidity (pKa)	2.223
Basicity (pKb)	11.777
Related compounds
Related alkanoic acids	Hopantenic acid; Hypusine; Saccharopine;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

4-(γ-Glutamylamino)butanoic acid is molecule that consists of L-glutamate conjugated to γ-aminobutyric acid (GABA). It is the substrate of the enzyme γ-glutamyl-γ-aminobutyrate hydrolase, which is involved in the biosynthesis of polyamines.[2]

References

"NSC609423 - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification. Retrieved 8 July 2012.
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H (2005). "A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12". J. Biol. Chem. 280 (6): 4602–8. doi:10.1074/jbc.M411114200. PMID 15590624.

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