5-Hydroxyhydantoin
5-Hydroxyhydantoin is an oxidation product of 2′-deoxycytidine. If not repaired, it may be processed by DNA polymerases that induce mutagenic processes.[1]
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IUPAC name
5-Hydroxy-2,4-imidazolidinedione | |
Other names
Glyoxalurea; Allanturic acid | |
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Properties | |
C3H4N2O3 | |
Molar mass | 116.076 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
- Gasparutto, Didier; Muller, Evelyne; Boiteux, Serge; Cadet, Jean (January 2009). "Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N-glycosylases". Biochimica et Biophysica Acta (BBA) - General Subjects. 1790 (1): 16–24. doi:10.1016/j.bbagen.2008.10.001. PMID 18983898.
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