5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase
5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase (EC 2.1.1.245, cdhD (gene), cdhE (gene)) is an enzyme with systematic name 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein methyltransferase.[1][2] This enzyme catalyses the following chemical reaction:
- [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin
| 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.245 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.
References
- Maupin-Furlow J, Ferry JG (January 1996). "Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila". Journal of Bacteriology. 178 (2): 340–6. PMC 177663. PMID 8550451.
- Grahame DA, DeMoll E (April 1996). "Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex from Methanosarcina barkeri". The Journal of Biological Chemistry. 271 (14): 8352–8. doi:10.1074/jbc.271.14.8352. PMID 8626532.
External links
- 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur+protein+Co-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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