ABRA (gene)

Actin-binding Rho-activating protein is a protein that in humans is encoded by the ABRA gene.[5] The mouse and rat homologues are known as STARS (striated muscle activator of Rho signalling) and MS1 (myocyte stress 1) respectively.[6]

ABRA
Identifiers
AliasesABRA, STARS, actin binding Rho activating protein
External IDsOMIM: 609747 MGI: 2444891 HomoloGene: 34713 GeneCards: ABRA
Orthologs
SpeciesHumanMouse
Entrez

137735

223513

Ensembl

ENSG00000174429

ENSMUSG00000042895

UniProt

Q8N0Z2

Q8BUZ1

RefSeq (mRNA)

NM_139166

NM_175456

RefSeq (protein)

NP_631905

NP_780665

Location (UCSC)Chr 8: 106.76 – 106.77 MbChr 15: 41.73 – 41.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


MS1/STARS is regulated by MyoD during myogenic differentiation of the C2C12 cell line.

References

  1. GRCh38: Ensembl release 89: ENSG00000174429 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042895 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Arai A, Spencer JA, Olson EN (Jul 2002). "STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription". J Biol Chem. 277 (27): 24453–9. doi:10.1074/jbc.M202216200. PMID 11983702.
  6. "Entrez Gene: ABRA actin-binding Rho activating protein".

Further reading


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