ADAMTSL4

ADAMTS-like protein 4 is a protein that in humans is encoded by the ADAMTSL4 gene.[5][6]

ADAMTSL4
Identifiers
AliasesADAMTSL4, ADAMTSL-4, ECTOL2, TSRC1, ADAMTS like 4
External IDsOMIM: 610113 MGI: 2389008 HomoloGene: 23141 GeneCards: ADAMTSL4
Orthologs
SpeciesHumanMouse
Entrez

54507

229595

Ensembl

ENSG00000143382

ENSMUSG00000015850

UniProt

Q6UY14

Q80T21

RefSeq (mRNA)

NM_001288607
NM_001288608
NM_019032
NM_025008
NM_001378596

NM_001301705
NM_144899

RefSeq (protein)

NP_001275536
NP_001275537
NP_061905
NP_079284
NP_001365525

NP_001288634
NP_659148

Location (UCSC)Chr 1: 150.55 – 150.56 MbChr 3: 95.58 – 95.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000143382 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000015850 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Buchner DA, Meisler MH (Mar 2003). "TSRC1, a widely expressed gene containing seven thrombospondin type I repeats". Gene. 307: 23–30. doi:10.1016/S0378-1119(03)00423-2. PMID 12706885.
  6. "Entrez Gene: ADAMTSL4 ADAMTS-like 4".

Further reading

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