AHCYL1

Putative adenosylhomocysteinase 2 is an enzyme that in humans is encoded by the AHCYL1 gene.[5][6][7][8]

AHCYL1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAHCYL1, DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA, adenosylhomocysteinase like 1
External IDsOMIM: 607826 MGI: 2385184 HomoloGene: 77353 GeneCards: AHCYL1
Orthologs
SpeciesHumanMouse
Entrez

10768

229709

Ensembl

ENSG00000168710

ENSMUSG00000027893

UniProt

O43865

Q80SW1

RefSeq (mRNA)

NM_001242673
NM_001242674
NM_001242675
NM_001242676
NM_006621

NM_145542
NM_001357110
NM_001357111
NM_001357112
NM_001357113

RefSeq (protein)

NP_001229602
NP_001229603
NP_001229604
NP_001229605
NP_006612

NP_663517
NP_001344039
NP_001344040
NP_001344041
NP_001344042

Location (UCSC)Chr 1: 109.98 – 110.02 MbChr 3: 107.57 – 107.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

AHCYL1 has been shown to interact with ITPR1.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000168710 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027893 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Dekker JW, Budhia S, Angel NZ, Cooper BJ, Clark GJ, Hart DN, Kato M (Mar 2002). "Identification of an S-adenosylhomocysteine hydrolase-like transcript induced during dendritic cell differentiation". Immunogenetics. 53 (12): 993–1001. doi:10.1007/s00251-001-0402-z. PMID 11904675. S2CID 21593928.
  6. Cooper BJ, Key B, Carter A, Angel NZ, Hart DN, Kato M (Aug 2006). "Suppression and overexpression of adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) influences zebrafish embryo development: a possible role for AHCYL1 in inositol phospholipid signaling". J Biol Chem. 281 (32): 22471–84. doi:10.1074/jbc.M602520200. PMID 16754674.
  7. Ando H, Mizutani A, Matsu-ura T, Mikoshiba K (Mar 2003). "IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor". J Biol Chem. 278 (12): 10602–12. doi:10.1074/jbc.M210119200. PMID 12525476.
  8. "Entrez Gene: AHCYL1 S-adenosylhomocysteine hydrolase-like 1".

Further reading


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