APBB1IP

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP), also known as APBB1-interacting protein 1 or Rap1-GTP-interacting adapter molecule (RIAM) is a protein that in humans is encoded by the APBB1IP gene.[5][6][7]

APBB1IP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAPBB1IP, amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein, INAG1, PREL1, RARP1, RIAM, amyloid beta precursor protein binding family B member 1 interacting protein
External IDsOMIM: 609036 MGI: 1861354 HomoloGene: 32434 GeneCards: APBB1IP
Orthologs
SpeciesHumanMouse
Entrez

54518

54519

Ensembl

ENSG00000077420

ENSMUSG00000026786

UniProt

Q7Z5R6

Q8R5A3

RefSeq (mRNA)

NM_019043

NM_019456

RefSeq (protein)

NP_061916

NP_062329

Location (UCSC)Chr 10: 26.44 – 26.57 MbChr 2: 22.66 – 22.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000077420 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026786 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: amyloid beta (A4) precursor protein-binding".
  6. Inagaki T, Suzuki S, Miyamoto T, Takeda T, Yamashita K, Komatsu A, Yamauchi K, Hashizume K (December 2003). "The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells". J. Biol. Chem. 278 (51): 51685–92. doi:10.1074/jbc.M308016200. PMID 14530287.
  7. Lafuente EM, van Puijenbroek AA, Krause M, Carman CV, Freeman GJ, Berezovskaya A, Constantine E, Springer TA, Gertler FB, Boussiotis VA (October 2004). "RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion". Dev. Cell. 7 (4): 585–95. doi:10.1016/j.devcel.2004.07.021. hdl:1721.1/83508. PMID 15469846.

Further reading


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