APOA1BP

Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the APOA1BP gene.[5]

NAXE
Identifiers
AliasesNAXE, AIBP, YJEFN1, APOA1BP, NAD(P)HX epimerase, PEBEL
External IDsOMIM: 608862 MGI: 2180167 HomoloGene: 70948 GeneCards: NAXE
Orthologs
SpeciesHumanMouse
Entrez

128240

246703

Ensembl

ENSG00000163382

ENSMUSG00000028070

UniProt

Q8NCW5

Q8K4Z3

RefSeq (mRNA)

NM_144772

NM_144897

RefSeq (protein)

NP_658985

NP_659146

Location (UCSC)Chr 1: 156.59 – 156.61 MbChr 3: 87.96 – 87.97 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

APOA1BP binds to APOA1, APOA2, and high-density lipoprotein (HDL).[5] In addition, APOA1BP appears to play a role in sperm capacitation.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000163382 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028070 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ritter M, Buechler C, Boettcher A, Barlage S, Schmitz-Madry A, Orsó E, Bared SM, Schmiedeknecht G, Baehr CH, Fricker G, Schmitz G (May 2002). "Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I". Genomics. 79 (5): 693–702. doi:10.1006/geno.2002.6761. PMID 11991719.
  6. Jha KN, Shumilin IA, Digilio LC, Chertihin O, Zheng H, Schmitz G, Visconti PE, Flickinger CJ, Minor W, Herr JC (May 2008). "Biochemical and Structural Characterization of Apolipoprotein A-I Binding Protein, a Novel Phosphoprotein with a Potential Role in Sperm Capacitation". Endocrinology. 149 (5): 2108–20. doi:10.1210/en.2007-0582. PMC 2329272. PMID 18202122.
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