ASAHL

N-acylethanolamine-hydrolyzing acid amidase is an enzyme that in humans is encoded by the NAAA gene.[5][6][7]

NAAA
Identifiers
AliasesNAAA, ASAHL, PLT, N-acylethanolamine acid amidase
External IDsOMIM: 607469 MGI: 1914361 HomoloGene: 8686 GeneCards: NAAA
Orthologs
SpeciesHumanMouse
Entrez

27163

67111

Ensembl

ENSG00000138744

ENSMUSG00000029413

UniProt

Q02083

Q9D7V9

RefSeq (mRNA)

NM_001042402
NM_014435
NM_001363719

NM_001163687
NM_025972

RefSeq (protein)

NP_001035861
NP_055250
NP_001350648

NP_001157159
NP_080248

Location (UCSC)Chr 4: 75.91 – 75.94 MbChr 5: 92.41 – 92.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000138744 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029413 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hong SB, Li CM, Rhee HJ, Park JH, He X, Levy B, Yoo OJ, Schuchman EH (Feb 2000). "Molecular cloning and characterization of a human cDNA and gene encoding a novel acid ceramidase-like protein". Genomics. 62 (2): 232–41. doi:10.1006/geno.1999.5953. PMID 10610717.
  6. Goodchild NL, Wilkinson DA, Mager DL (Dec 1992). "A human endogenous long terminal repeat provides a polyadenylation signal to a novel, alternatively spliced transcript in normal placenta". Gene. 121 (2): 287–94. doi:10.1016/0378-1119(92)90133-A. PMID 1446826.
  7. "Entrez Gene: ASAHL N-acylsphingosine amidohydrolase (acid ceramidase)-like".

Further reading


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