Aconitate Delta-isomerase

In enzymology, an aconitate Δ-isomerase (EC 5.3.3.7) is an enzyme that catalyzes the chemical reaction

trans-aconitate cis-aconitate
Aconitate Δ-isomerase
Identifiers
EC no.5.3.3.7
CAS no.37318-48-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Hence, this enzyme has one substrate, trans-aconitate, and one product, cis-aconitate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is aconitate Delta2-Delta3-isomerase. This enzyme is also called aconitate isomerase.

References

    • Klinman JP; Rose IA (1971). "Purification and kinetic properties of aconitate isomerase from Pseudomonas putida". Biochemistry. 10 (12): 2253–2259. doi:10.1021/bi00788a011. PMID 5114987.
    • Klinman JP, Rose IA (1971). "Mechanism of the aconitate isomerase reaction". Biochemistry. 10 (12): 2259–66. doi:10.1021/bi00788a012. PMID 5114988.


    This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.