Alexidine
Alexidine is an antimicrobial of the biguanide class.[1] More specifically, it is a bisbiguanide.[2]
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Preferred IUPAC name
N1,N1′-(Hexane-1,6-diyl)bis[N3-(2-ethylhexyl)imidodicarbonic diamide] | |
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3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.040.981 |
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KEGG | |
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CompTox Dashboard (EPA) |
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Properties | |
C26H56N10 | |
Molar mass | 508.804 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
References
- Barrios, Rocío; Ferrer-Luque, Carmen María; Arias-Moliz, María Teresa; Ruiz-Linares, Matilde; Bravo, Manuel; Baca, Pilar (November 2013). "Antimicrobial substantivity of alexidine and chlorhexidine in dentin". J Endod. 39 (11): 1413–5. doi:10.1016/j.joen.2013.07.038. PMID 24139264.
- Tanzer JM, Slee AM, Kamay BA (1977). "Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque activity". Antimicrob. Agents Chemother. 12 (6): 721–9. doi:10.1128/aac.12.6.721. PMC 430011. PMID 931371.
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