Aminotransferase, class V

Aminotransferase class-V is an evolutionary conserved protein domain. This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.

Aminotransferase class-V
Identifiers
SymbolAminotran_5
PfamPF00266
InterProIPR000192
PROSITEPDOC00514
SCOP21bjo / SCOPe / SUPFAM
CDDcd00611
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1qz9A:30-392 1i29A:25-394 1c0nA:25-394

1jf9A:25-394 1kmjA:25-394 1t3iB:30-402 1eluB:97-273 1n31B:97-273 1elqB:97-273 1n2tA:97-273 1ecxB:3-365 1eg5B:3-365 1p3wA:5-369 2bkwA:8-370 1h0cA:23-376 1j04A:23-376 1vjoA:23-372 1iugB:2-337 1m32A:117-192 1bjnB:4-350 2bhxB:5-350 2biaA:5-350 2bi2A:5-350 2bi9A:5-350 2bigB:5-350 2bieA:5-350 2bi3B:5-350 2bi5B:5-350 1w23A:5-350 2bi1A:5-350

1w3uA:5-350 1bt4A:5-350

Aminotransferases share certain mechanistic features with other pyridoxal- phosphate dependent enzymes, such as the covalent binding of the pyridoxal- phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped[1] into subfamilies. This family is called class-V.

Subfamilies

Human proteins containing this domain

AGXT; KYNU; MOCOS; NFS1; PSAT1; SCLY; TLH6;

References
  1. Ouzounis C, Sander C (May 1993). "Homology of the NifS family of proteins to a new class of pyridoxal phosphate-dependent enzymes". FEBS Letters. 322 (2): 159–64. doi:10.1016/0014-5793(93)81559-I. PMID 8482384. S2CID 14587217.
This article incorporates text from the public domain Pfam and InterPro: IPR000192
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