Apalachicola

Apalachicola may refer to:

• Apalachicola band, an association of Native American towns along the Apalachicola River in Florida in the early 19th century
• Apalachicola Province, an association of Native American towns on the Chattahoochee River in Alabama and Georgia that became the Lower Towns of the Muscogee Confederacy
• Apalachicola (tribal town), a Native American town that was the namesake of the Apalachicola Province