Armadillo repeat containing 12

Armadillo repeat containing 12 is a protein that in humans is encoded by the ARMC12 gene[5] that plays a crucial role in tumor progression. It is associated with the development of neuroblastoma (NB) as it encourages the growth and aggressiveness of NB cell lines.[6]

ARMC12
Identifiers
AliasesARMC12, C6orf81, armadillo repeat containing 12
External IDsMGI: 1914895 HomoloGene: 12168 GeneCards: ARMC12
Orthologs
SpeciesHumanMouse
Entrez

221481

67645

Ensembl

ENSG00000157343

ENSMUSG00000024223

UniProt

Q5T9G4

Q80X86

RefSeq (mRNA)

NM_001286574
NM_001286576
NM_145028

NM_026290

RefSeq (protein)

NP_001273503
NP_001273505
NP_659465

NP_080566

Location (UCSC)Chr 6: 35.74 – 35.75 MbChr 17: 28.75 – 28.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000157343 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000024223 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Armadillo repeat containing 12". Retrieved 2017-12-22.
  6. Li D, Song H, Mei H, Fang E, Wang X, Yang F, Li H, Chen Y, Huang K, Zheng L, Tong Q (July 2018). "Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4". Nature Communications. 9 (1): 2829. doi:10.1038/s41467-018-05286-2. PMC 6053364. PMID 30026490.


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