Armadillo repeat containing 12

ARMC12
Identifiers
Aliases	ARMC12, C6orf81, armadillo repeat containing 12
External IDs	MGI: 1914895 HomoloGene: 12168 GeneCards: ARMC12
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	35,749,079 bp[1]
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)[2]
End	28,758,084 bp[2]
RNA expression pattern
	Top expressed in
	anterior pituitary; ; sperm; ; right lobe of liver; ; left uterine tube; ; right adrenal gland; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; nucleus accumbens; ; gastric mucosa; ; putamen;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; morula; ; secondary oocyte; ; yolk sac; ; proximal tubule; ; superior frontal gyrus; ; cerebellar cortex; ; kidney;
	More reference expression data
	n/a
Orthologs
	221481
	67645
	ENSG00000157343
	ENSMUSG00000024223
	Q5T9G4
	Q80X86
	NM_001286574; NM_001286576; NM_145028
	NM_026290
	NP_001273503; NP_001273505; NP_659465
	NP_080566
	Wikidata
View/Edit Human	View/Edit Mouse

Armadillo repeat containing 12 is a protein that in humans is encoded by the ARMC12 gene[5] that plays a crucial role in tumor progression. It is associated with the development of neuroblastoma (NB) as it encourages the growth and aggressiveness of NB cell lines.[6]

References

GRCh38: Ensembl release 89: ENSG00000157343 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000024223 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Armadillo repeat containing 12". Retrieved 2017-12-22.
Li D, Song H, Mei H, Fang E, Wang X, Yang F, Li H, Chen Y, Huang K, Zheng L, Tong Q (July 2018). "Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4". Nature Communications. 9 (1): 2829. doi:10.1038/s41467-018-05286-2. PMC 6053364. PMID 30026490.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000157343 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024223 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Armadillo repeat containing 12". Retrieved 2017-12-22.

[pmid30026490-6] Li D, Song H, Mei H, Fang E, Wang X, Yang F, Li H, Chen Y, Huang K, Zheng L, Tong Q (July 2018). "Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4". Nature Communications. 9 (1): 2829. doi:10.1038/s41467-018-05286-2. PMC 6053364. PMID 30026490.