Arylomycin A2

Arylomycin A2 is a synthetic antibiotic of the arylomycin class.[2][3]

Arylomycin A2
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C32H40N6O11/c1-15(34-30(46)23(14-39)37(4)17(3)40)28(44)33-13-26(43)38(5)27-19-7-9-25(42)21(12-19)20-10-18(6-8-24(20)41)11-22(32(48)49)36-29(45)16(2)35-31(27)47/h6-10,12,15-16,22-23,27,39,41-42H,11,13-14H2,1-5H3,(H,33,44)(H,34,46)(H,35,47)(H,36,45)(H,48,49)/t15-,16+,22+,23-,27+/m1/s1
    Key: TUPFYYWHWXBPLS-YGBZZOJMSA-N
  • C[C@H]1C(=O)N[C@@H](Cc2ccc(c(c2)-c3cc(ccc3O)[C@@H](C(=O)N1)N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](CO)N(C)C(=O)C)O)C(=O)O
Properties
C32H40N6O11
Molar mass 684.703 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. "KNApSAcK Metabolite Information - C00015060". www.knapsackfamily.com.
  2. Roberts, T. C.; Smith, P. A.; Cirz, R. T.; Romesberg, F. E. (2007). "Structural and initial biological analysis of synthetic arylomycin A2". Journal of the American Chemical Society. 129 (51): 15830–8. doi:10.1021/ja073340u. PMID 18052061.
  3. Dufour, Jeremy; Neuville, Luc; Zhu, Jieping (2010). "Intramolecular Suzuki–Miyaura Reaction for the Total Synthesis of Signal Peptidase Inhibitors, Arylomycins A2 and B2". Chemistry - A European Journal. 16 (34): 10523–34. doi:10.1002/chem.201000924. PMID 20658499.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.