Asif Ahmed (scientist)

Asif Ahmed FRSB is a British-Indian vascular scientist,[1] whose research focuses on reducing the risk of mortality and morbidity in pregnancy.[2] He is the founder and former Pro-Vice-Chancellor and Executive Dean of Aston Medical School, Birmingham,[3] and established the Aston Medical Research Institute, a university-wide multidisciplinary translational research entity at Aston University.[4]

Asif Ahmed
Asif Ahmed at the Aston University in 2016
NationalityBritish
Alma mater
Scientific career
FieldsPreeclampsia
Institutions
ThesisPlatelet abnormalities in cardiopulmonary bypass surgery (1989)
Doctoral advisors
  • Paul Salmon
  • Michael Hobsley
Other academic advisors

Education and career

Asif Ahmed went to a local comprehensive Aylward School in North London and was subsequently educated at King's College London where he gained his undergraduate degree in pharmacology. He was awarded a Ph.D. for his work on platelet abnormalities in cardiopulmonary bypass surgery from University College London in 1989.[5]

From 1989 to 1993, he was a Postdoctoral Research Fellow at the University of Cambridge and went on to work at The University of Birmingham, being promoted to Professor of Reproductive Physiology in 1998. From 2009 to 2011 he was a Visiting Professor at Stanford University School of Medicine.[6]

He held the Inaugural Gustav Born Chair of Vascular Biology[7] and was appointed as the Assistant Principal for International Postdoctoral Training at the University of Edinburgh in 2010.[8] Ahmed joined Aston University as the first Pro-Vice-Chancellor for Health in October 2012.[9] He was elected as a Fellow of the Royal Society of Biology in 2013.

As of 2021, he is Senior Advisor to the President and Vice-Chancellor at the University of Southampton.[10]

Research

Ahmed's laboratory has studied vascular growth factors in pregnancy and preeclampsia.[11] Research topics include the enzyme placental heme oxygenase (HO),[12] carbon monoxide (CO),[13][14] and soluble Flt-1.[15][16]

References
  1. "Asif Ahmed". scholar.google.com. Retrieved 23 March 2023.
  2. "Cure for pre-eclampsia? Birmingham scientist offers hope for millions of women". 28 October 2020.
  3. Aston Medical School
  4. "Aston Medical Research Institute". Retrieved 23 March 2023.
  5. "ORCID". orcid.org. Retrieved 23 March 2023.
  6. "Times Higher Education". 10 January 2013.
  7. "Gustav's Edinburgh Memories". The University of Edinburgh. Retrieved 23 March 2023.
  8. "University of Edinburgh" (PDF). Retrieved 23 March 2023.
  9. "Appointments". 10 January 2013.
  10. "Professor Asif Ahmed PhD". University of Southampton. Retrieved 11 December 2021.
  11. Ahmed, A; Dunk, C; Kniss, D; Wilkes, M (1997). "Role of VEGF receptor-1 (Flt-1) in mediating calcium-dependent nitric oxide release and limiting DNA synthesis in human trophoblast cells". Laboratory Investigation; A Journal of Technical Methods and Pathology. 76 (6): 779–91. PMID 9194854.
  12. Ahmed, A; Rahman, M; Zhang, X; Acevedo, C. H; Nijjar, S; Rushton, I; Bussolati, B; St John, J (2000). "Induction of placental heme oxygenase-1 is protective against TNFalpha-induced cytotoxicity and promotes vessel relaxation". Molecular Medicine. 6 (5): 391–409. doi:10.1007/bf03401783. PMC 1949957. PMID 10952020.
  13. Cudmore, M; Ahmad, S; Al-Ani, B; Fujisawa, T; Coxall, H; Chudasama, K; Devey, L. R; Wigmore, S. J; Abbas, A; Hewett, P. W; Ahmed, A (2007). "Negative Regulation of Soluble Flt-1 and Soluble Endoglin Release by Heme Oxygenase-1". Circulation. 115 (13): 1789–97. doi:10.1161/CIRCULATIONAHA.106.660134. PMID 17389265.
  14. Wang, K; Ahmad, S; Cai, M; Rennie, J; Fujisawa, T; Crispi, F; Baily, J; Miller, M. R; Cudmore, M; Hadoke, P. W. F; Wang, R; Gratacos, E; Buhimschi, I. A; Buhimschi, C. S; Ahmed, A (2013). "Dysregulation of Hydrogen Sulfide Producing Enzyme Cystathionine -lyase Contributes to Maternal Hypertension and Placental Abnormalities in Preeclampsia". Circulation. 127 (25): 2514–22. doi:10.1161/CIRCULATIONAHA.113.001631. PMID 23704251.
  15. Ahmad, S; Ahmed, A (2004). "Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia". Circulation Research. 95 (9): 884–91. doi:10.1161/01.RES.0000147365.86159.f5. PMID 15472115.
  16. Thadhani, R; Kisner, T; Hangman, H; Bossung, V; Noack, S; Schaarschmidt, W; Jank, A; Kribs, A; Cornely, OA; Kreyssig, C; Hemphill, L; Rigby, AC; Khedkar, S; Lindner, TH; Mallmann, P; Stepan, H; Karumanchi, SA; Benzing, T (2011). "Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia". Circulation. 124 (4): 940–50. doi:10.1161/CIRCULATIONAHA.111.034793. PMID 21810665.
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