B3GALTL

B3GLCT
Identifiers
Aliases	B3GLCT, B3GTL, B3Glc-T, Gal-T, beta3Glc-T, B3GALTL, beta 3-glucosyltransferase
External IDs	OMIM: 610308 MGI: 2685903 HomoloGene: 14978 GeneCards: B3GLCT
Gene location (Human)
Chr.	Chromosome 13 (human)[1]
End	31,332,276 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	149,686,064 bp[2]
RNA expression pattern
	Top expressed in
	Achilles tendon; ; tibialis anterior muscle; ; smooth muscle tissue; ; endothelial cell; ; stromal cell of endometrium; ; caudate nucleus; ; putamen; ; nucleus accumbens; ; popliteal artery; ; left uterine tube;
	Top expressed in
	ciliary body; ; iris; ; trigeminal ganglion; ; retinal pigment epithelium; ; otolith organ; ; utricle; ; ascending aorta; ; hand; ; vas deferens; ; ureter;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; glycosyltransferase activity; acetylglucosaminyltransferase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane;
Biological process	fucose metabolic process; protein glycosylation; protein O-linked fucosylation; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	145173
	381694
	ENSG00000187676
	ENSMUSG00000051950
	Q6Y288
	Q8BHT6
	NM_194318
	NM_001081204
	NP_919299
	NP_001074673
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-1,3-glucosyltransferase is an enzyme that in humans is encoded by the B3GALTL gene.[5][6][7][8]

References

GRCh38: Ensembl release 89: ENSG00000187676 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000051950 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Heinonen TY, Pasternack L, Lindfors K, Breton C, Gastinel LN, Maki M, Kainulainen H (Aug 2003). "A novel human glycosyltransferase: primary structure and characterization of the gene and transcripts". Biochem Biophys Res Commun. 309 (1): 166–174. doi:10.1016/S0006-291X(03)01540-7. PMID 12943678.
Sato T, Sato M, Kiyohara K, Sogabe M, Shikanai T, Kikuchi N, Togayachi A, Ishida H, Ito H, Kameyama A, Gotoh M, Narimatsu H (Nov 2006). "Molecular cloning and characterization of a novel human beta1,3-glucosyltransferase, which is localized at the endoplasmic reticulum and glucosylates O-linked fucosylglycan on thrombospondin type 1 repeat domain". Glycobiology. 16 (12): 1194–1206. doi:10.1093/glycob/cwl035. PMID 16899492.
Kozma K, Keusch JJ, Hegemann B, Luther KB, Klein D, Hess D, Haltiwanger RS, Hofsteenge J (Nov 2006). "Identification and characterization of abeta1,3-glucosyltransferase that synthesizes the Glc-beta1,3-Fuc disaccharide on thrombospondin type 1 repeats". J Biol Chem. 281 (48): 36742–36751. doi:10.1074/jbc.M605912200. PMID 17032646.
"Entrez Gene: B3GALTL beta 1,3-galactosyltransferase-like".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–528. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Lesnik Oberstein SA, Kriek M, White SJ, et al. (2006). "Peters Plus syndrome is caused by mutations in B3GALTL, a putative glycosyltransferase". Am. J. Hum. Genet. 79 (3): 562–566. doi:10.1086/507567. PMC 1559553. PMID 16909395.

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