BAIAP3

BAI1-associated protein 3 is a protein that in humans is encoded by the BAIAP3 gene.[5][6]

BAIAP3
Identifiers
AliasesBAIAP3, BAP3, BAI1 associated protein 3
External IDsOMIM: 604009 MGI: 2685783 HomoloGene: 20844 GeneCards: BAIAP3
Orthologs
SpeciesHumanMouse
Entrez

8938

545192

Ensembl

ENSG00000007516

ENSMUSG00000047507

UniProt

O94812

Q80TT2

RefSeq (mRNA)

NM_001163270

RefSeq (protein)

n/a

Location (UCSC)Chr 16: 1.33 – 1.35 MbChr 17: 25.46 – 25.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BAIAP3 was identified as a protein-binding partner of BAI1. BAI1 is a p53-target gene that encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. BAIAP3 interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. BAIAP3 also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions.[6]

Interactions

BAIAP3 has been shown to interact with Brain-specific angiogenesis inhibitor 1.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000007516 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000047507 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Shiratsuchi T, Oda K, Nishimori H, Suzuki M, Takahashi E, Tokino T, Nakamura Y (Nov 1998). "Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1". Biochem Biophys Res Commun. 251 (1): 158–65. doi:10.1006/bbrc.1998.9408. PMID 9790924.
  6. "Entrez Gene: BAIAP3 BAI1-associated protein 3".

Further reading


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