BMP binding endothelial regulator

BMP binding endothelial regulator is a protein that in humans is encoded by the BMPER gene.[5]

BMPER
Identifiers
AliasesBMPER, CRIM3, CV-2, CV2, BMP binding endothelial regulator
External IDsOMIM: 608699 MGI: 1920480 HomoloGene: 12494 GeneCards: BMPER
Orthologs
SpeciesHumanMouse
Entrez

168667

73230

Ensembl

ENSG00000164619

ENSMUSG00000031963

UniProt

Q8N8U9

Q8CJ69

RefSeq (mRNA)

NM_133468
NM_001365308

NM_028472

RefSeq (protein)

NP_597725

NP_082748

Location (UCSC)Chr 7: 33.9 – 34.16 MbChr 9: 23.13 – 23.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transcription

KLF15 is a strong and direct activator of BMPER expression which is inhibited by SP1. BMPER is inhibited by endothelin-1, which may be mediated by endothelin inhibition of KLF15.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000164619 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000031963 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: BMP binding endothelial regulator". Retrieved 2011-09-29.
  6. Helbing T, Volkmar F, Goebel U, Heinke J, Diehl P, Pahl HL, Bode C, Patterson C, Moser M (Feb 2010). "Krüppel-like factor 15 regulates BMPER in endothelial cells". Cardiovascular Research. 85 (3): 551–9. doi:10.1093/cvr/cvp314. PMC 4110462. PMID 19767294.

Further reading


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