Beta-eudesmol synthase

β-Eudesmol synthase (EC 4.2.3.68) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (β-eudesmol-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O β-eudesmol + diphosphate
β-eudesmol synthase
Identifiers
EC no.4.2.3.68
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The recombinant enzyme from ginger (Zingiber zerumbet) gives β-eudesmol, 10-epi-γ-eudesmol, α-eudesmol and aristolene.

References

  1. Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, Misawa N, Utsumi R (March 2008). "Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith". FEBS Letters. 582 (5): 565–72. doi:10.1016/j.febslet.2008.01.020. PMID 18242187.
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