Bicine

Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C.[1] It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.[2]

Bicine
Names
IUPAC name
N,N-Bis(2-hydroxyethyl)glycine
Systematic IUPAC name
[Bis(2-hydroxyethyl)amino]acetic acid
Other names
Diethylolglycine; Diethanol glycine; Dihydroxyethylglycine; BHG
Identifiers
3D model (JSmol)
Abbreviations DHEG
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.005.233
UNII
  • InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) checkY
    Key: FSVCELGFZIQNCK-UHFFFAOYSA-N checkY
  • InChI=1/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
    Key: FSVCELGFZIQNCK-UHFFFAOYAV
  • O=C(O)CN(CCO)CCO
Properties
C6H13NO4
Molar mass 163.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O2, SO2, H2S or Thiosulfate.[3]

See also

References
  1. N,N-Bis(2-hydroxyethyl)glycine at ChEBI
  2. The Merck Index (10th ed.). Rahway, NJ: Merck & Co. 1983. p. 453. ISBN 0-911910-27-1.
  3. Lawson, Gary (2003). "Amine Plant Corrosion Reduced by Removal of Bicine" (PDF). Gas Processors Association Annual Convention. Archived from the original (PDF) on 2015-06-16. Retrieved 18 March 2016.
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