Bisindolylmaleimide

Bisindolylmaleimide is an organic compound that forms the core chemical structure of a variety of biologically active compounds.[1] This core structure includes a central maleimide group with two indole groups attached.

Bisindolylmaleimide
Skeletal formula of bisindolylmaleimide
Space-filling model of the bisindolylmaleimide molecule
Names
Preferred IUPAC name
3,4-Di(1H-indol-2-yl)-1H-pyrrole-2,5-dione
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25)
    Key: LRBHDUWDZCAYDA-UHFFFAOYSA-N
  • InChI=1/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25)
    Key: LRBHDUWDZCAYDA-UHFFFAOYAH
  • O=C5C(\c2cc1ccccc1[nH]2)=C(\c4cc3ccccc3[nH]4)C(=O)N5
Properties
C20H13N3O2
Molar mass 327.343 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Examples of bisindolylmaleimide derivatives include:

References
  1. Faul, Margaret M.; Winneroski, Leonard L.; Krumrich, Christine A. (1998). "A New, Efficient Method for the Synthesis of Bisindolylmaleimides". The Journal of Organic Chemistry. 63 (17): 6053. doi:10.1021/jo980513c. PMID 11672217.

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